在一小批戈丘阿斯图尔塞尔塔猪的小血统中接近自性
Katherine D Arias1, Juan Pablo Gutiérrez2, Iván Fernández1
1Área de Genética y Reproducción Animal, SERIDA-Deva, Camino de Rioseco 1225, 33394, Gijón, Spain.
Genetics, selection, evolution : GSE
|October 25, 2023
概括
基因组数据有助于通过测量自囊性来评估遗传多样性,将其与内生育区分开来. 双相同性,从同性 (FROH) 或异性丰富区域 (FHRR) 的运行计算出来,是特征危品种遗传多样性的有希望的方法.
科学领域:
- 动物遗传学动物遗传学
- 保护基因组学 保护基因组学
- 人口遗传学 人口遗传学
背景情况:
- 尽管SNP数组数据可用,但区分自性和一般同性是很有挑战性的.
- 同胞性估计因孟德尔采样,人口结构和染色体差异而有所不同.
- 评估基因组内生育需要强大的方法来准确评估遗传多样性.
研究的目的:
- 评估基因组信息对评估临灭绝的戈丘阿斯图尔切尔塔猪品种遗传多样性的有用性.
- 为了比较不同的同卵性参数 (FROH,FHRR,FLH,FYAN) 以反映遗传多样性的有效性.
- 调查内生和有效种群大小 (Ne) 的基因组和基因谱估计之间的关系.
主要方法:
- 计算了每个人的四个同卵性参数 (FROH,FHRR,FLH,FYAN).
- 调整了基本人群变异性的同卵性参数,并对自体进行了刀.
- 计算的个体和对同性增加和有效人口大小 (Ne) 的子群.
主要成果:
- 平均血压调整后的同胞性在0.099 (FLH) 到0.152 (FYAN) 之间.
- 双对同性增加大约是个体同性增加的两倍.
- 与其他方法相比,使用对式同性 (FROH,FHRR) 的Ne估计显示出较低的根-平均-平方误差.
结论:
- 同胞性参数可能不准确地反映了严格的育种政策的小群体的遗传多样性损失.
- 在基数调整后,FROH和FHRR表现一致.
- 从FROH或FHRR计算的对同性增加是表征自性和遗传多样性的有希望的方法.
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