抗原鉴定对间歇性肺部疾病中无移植生存率的影响
Margaret Kypreos1, Kiran Batra2, Craig S Glazer3
1Division of Pulmonary and Critical Care Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX, 75219, USA. margaret.kypreos@utsouthwestern.edu.
BMC pulmonary medicine
|October 25, 2023
概括
抗原识别可以改善过敏性肺炎的生存率,但不能改善其他间歇性肺部疾病的生存率. 在抗原去除之前,对过敏性肺炎的最终诊断可能至关重要.
科学领域:
- 肺部病理学 肺部病理学
- 免疫学 免疫学 免疫学
- 医学诊断 医学诊断 医学诊断
背景情况:
- 抗原鉴定是诊断和预测过敏性肺炎的关键.
- 抗原识别在其他间歇性肺部疾病的生存中的作用尚不清楚.
研究的目的:
- 调查抗原识别是否影响各种间歇性肺部疾病的无移植生存率.
- 具体检查过敏性肺炎,异常性肺纤维化,结缔组织疾病间歇性肺病和具有自身免疫特征的间歇性肺炎.
主要方法:
- 追溯的队列分析.
- 纳入标准:符合美国胸腔学会指导方针的患者,具有明显或高概率的过敏性肺炎.
- 基于抗原识别的无移植生存率的评估.
主要成果:
- 抗原鉴定与过敏性肺炎的无移植生存率的改善有关.
- 对于异常性肺纤维化,结缔组织疾病间歇性肺病或具有自身免疫特征的间歇性肺炎的抗原鉴定,没有观察到显著的生存益处.
结论:
- 除去抗原可能不会改善除过敏性肺炎之外的间歇性肺部疾病的存活率.
- 建议在抗原去除之前对过敏性肺炎进行最终诊断,可能通过支气管支气管洗和横支气管活检.
更多相关视频
18:48In Vitro and In Vivo Assessment of T, B and Myeloid Cells Suppressive Activity and Humoral Responses from Transplant Recipients
Published on: August 12, 2017
14.4K
06:15Author Spotlight: Investigating the Key Factors of Obliterative Bronchiolitis After Lung Transplantation
Published on: November 10, 2023
912
相关概念视频
Cell-mediated Immune Responses
68.6K
Overview
68.6K
Kidney Transplant I: Introduction
14
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
14
Tissue Transplantation
379
Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
379
