肠道微生物群和自闭症谱系障碍:我们站在哪里?
Sa'ed H Zyoud1,2, Muna Shakhshir3, Amani S Abushanab4
1Department of Clinical and Community Pharmacy, College of Medicine and Health Sciences, An-Najah National University, 44839, Nablus, Palestine. saedzyoud@yahoo.com.
Gut pathogens
|October 26, 2023
概括
对肠道微生物群和自闭症谱系障碍 (ASD) 的研究正在迅速增长,研究重点关注肠道细菌调制作为ASD的潜在治疗方法. 这一领域对未来的治疗干预显著有前途.
科学领域:
- 微生物组研究的研究.
- 神经发育障碍 神经发育障碍
- 儿科卫生健康 儿科卫生健康
背景情况:
- 患有自闭症谱系障碍 (ASD) 的儿童经常经历消化问题和肠道微生物失衡.
- 这些胃肠道疾病可能有助于ASD的发展.
- 对Scopus索引研究的图书统计分析探索了肠道微生物群与ASD的联系.
研究的目的:
- 分析当前关于肠道微生物群和ASD的研究环境.
- 识别关键的研究趋势,有影响力的国家和机构.
- 确定这个新兴领域的潜在未来研究方向.
主要方法:
- 从Scopus数据库 (2003-2022) 中对958篇文章进行了图书统计分析.
- 使用VOSviewer可视化国际合作和研究热点.
- 包括参考引用分析来评估研究影响.
主要成果:
- 2013年后,关于肠道微生物群和ASD的出版物产量急剧增加,在2022年达到顶峰.
- 美国在出版方面处于领先地位,其次是中国和意大利,它们在国际上有着重要的合作.
- 关键的研究主题包括肠道微生物群调节用于ASD治疗和ASD的肠-大脑轴功能障碍.
结论:
- 与ASD相关的肠道微生物群的研究是一个快速扩展和重要的研究领域.
- 结果提供了知识格局的全面概述,并突出了有希望的未来研究途径.
- 建议增加投资,探索调节ASD儿童肠道微生物群的治疗潜力.
相关概念视频
Autism Spectrum Disorder
104
Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
104
Anatomy of the Intestines
72.2K
Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
72.2K
Irritable Bowel Syndrome I: Introduction
284
Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
284
What is Monogastric Digestion?
71.3K
The human body contains a monogastric digestive system. In a monogastric digestive system, the stomach only contains one chamber in which it digests food. Several other animal species also have monogastric digestive systems, including pigs, horses, dogs, and birds. This chapter, however, focuses on the human digestive system.
71.3K


