吸入的β2agonist,formoterol,增强了精英骑自行车运动员的强烈运动表现和冲刺能力
Jan S Jeppesen1, Søren Jessen1, Martin Thomassen1
1The August Krogh Section for Human Physiology, Department of Nutrition, Exercise and Sports (NEXS), University of Copenhagen, Copenhagen, Denmark.
Scandinavian journal of medicine & science in sports
|October 26, 2023
概括
吸入形式特醇 (54μg) 在精英男性骑自行车运动员中显著提高了冲刺和短时间强度运动的表现. 这种性能提升独立于训练状态,但部分与特定的肌肉纤维类型有关.
科学领域:
- 运动生理学 运动生理学
- 运动科学 运动科学 运动科学
- 药理学 药理学是指药理学的学科.
背景情况:
- 长效β2-激动剂如formoterol用于运动员的喘.
- 以前的研究表明,吸入formoterol可能会提高非运动员的冲刺表现.
- 这引发了关于其在竞技运动中的使用和潜在限制的问题.
研究的目的:
- 研究高吸入剂量 (54μg) 甲醇对精英骑自行车运动员冲刺能力和强度运动表现的影响.
- 为了确定是否formoterol在受过高度训练的运动员群体中提高了表现.
主要方法:
- 21名精英男子骑自行车者进行了两次6秒全力冲刺和一个4分钟全力骑自行车测试.
- 在测试之前,参与者吸入了54μg的formoterol或安慰剂.
- 评估了腿部肌肉质量和巨大的横向肌肉纤维类型分布.
主要成果:
- 在6秒的冲刺中,formoterol显著增加了峰值和平均功率输出,约3% (p<0.001).
- 在4分钟的全力循环中,用formoterol (p=0.01) 的功率输出也增加了2.3%.
- 性能改善与VO2max或腿筋量无关,但冲刺表现与I型肌肉纤维分布相关.
结论:
- 单次吸入的54μg形式醇剂量可提高精英男性骑自行车运动员的冲刺和短期强度运动表现.
- 提高表现的效果独立于骑自行车者的训练状态.
- 性能提升的程度,特别是在短跑中,部分与个体的肌肉纤维类型分布有关.
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