了解肥胖和阻塞性睡眠呼吸暂停综合征之间的关联:一个案例对照研究
Kuldeep Patial1, Hara Prasad Mishra2,3, Giridhari Pal4
1Sleep Medicine, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, IND.
Cureus
|October 26, 2023
概括
阻塞性睡眠呼吸暂停 (OSA) 与肥胖症标志物有很强的联系. 解决与肥胖相关的人类测量变化可能会改善OSA症状.
科学领域:
- 睡眠医学 睡眠医学
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 是一种影响上呼吸道功能的睡眠障碍.
- 无论是因果关系还是相关性,OSA和肥胖之间的关系需要进一步调查.
- 共同的潜在因素可能会导致OSA和肥胖.
研究的目的:
- 为了研究阻塞性睡眠呼吸暂停综合征 (OSAS) 和肥胖之间的相互作用.
- 分析OSA患者和健康对照组的人类测量数据.
主要方法:
- 一项涉及40名OSA患者和40名匹配对照者的病例控制研究.
- 综合的人类测量评估包括身高,体重,BMI以及各种周长和皮肤折叠测量.
- 纳入标准:报告的打,白天嗜睡,或两者兼而有之.
主要成果:
- 在OSA患者中,腰围,腰比和脂肪分布 (内脏,皮下,干部,腿部) 存在显著差异.
- 在OSA患者的双肩,三,下和上部位增加皮肤折叠厚度.
- 虽然一些人体指标,如BMI和子周长在OSA患者中较高,但统计学意义并不总是达到.
结论:
- 在OSA和各种肥胖标志物之间存在显著的相关性.
- 针对与肥胖相关的人类测量变量可能为OSA症状管理提供治疗策略.
- 针对肥胖的药理干预可能有助于缓解OSA症状.
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