成年严重喘登记:一个全球和不断增长的库存
Breda Cushen1, Mariko Siyue Koh2, Trung N Tran3
1Department of Respiratory Medicine, Beaumont Hospital, Dublin, Ireland.
Pragmatic and observational research
|October 26, 2023
概括
在国际严重喘登记处 (ISAR) 内外,在严重喘登记处进行标准化数据收集,增强了全球研究能力. 这种方法统一了数据,增加了全球严重喘研究的统计能力.
科学领域:
- 肺病学和呼吸系统医学
- 流行病学和公共卫生.
- 临床研究方法论 临床研究方法论
背景情况:
- 严重的喘研究需要强大的,多国数据来实现足够的统计能力.
- 国际严重喘登记处 (ISAR) 促进用于严重喘研究的标准化数据收集.
- 全球合作对于解决严重喘管理和治疗的复杂性至关重要.
研究的目的:
- 为了比较ISAR和非ISAR注册表之间的数据收集实践.
- 确定全球严重喘登记处收集的共同和独特的数据点.
- 评估标准化数据的潜力,以支持全球研究和个别国家的严重喘利益.
主要方法:
- 通过在线搜索和专家咨询,确定了严重喘登记.
- 收集了来自参与注册的数据收集规范和确认的变量.
- 总结了核心的收集,类固醇相关的并发症,生物安全,COVID-19,以及其他变量,包括问卷和链接的数据库数据.
主要成果:
- 37个注册表被确定 (26个ISAR,11个非ISAR);25个ISAR和4个非ISAR注册表收集了65个核心变量的90%以上.
- 报告了可选类固醇相关并发症 (23) 和安全 (29) 变量的高收集率.
- 还收集了COVID-19 (10),包括各种喘问卷 (例如ACQ,ACT,AQLQ) 和链接数据库 (8) 的数据.
结论:
- 标准化数据收集使得严重喘登记处能够收集统一的数据.
- 这种标准化增加了严重喘研究的统计能力.
- 标准化数据收集的好处是不论ISAR的附属关系都能实现,支持全球研究工作.
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