我们如何管理一个高的D-二次体
Massimo Franchini1, Daniele Focosi2, Mario Piergiulio Pezzo1
1Department of Transfusion Medicine and Hematology, Carlo Poma Hospital, Mantova, Italy.
Haematologica
|October 26, 2023
概括
升高的D-二聚体水平,血块分解的标志物,可以发生在除了静脉血栓塞栓症 (VTE) 的许多条件. 本综述指导了血液学家在管理没有VTE症状的高D-二次体患者.
科学领域:
- 血液学 血液学 血液学
- 凝血科学 凝血科学
- 生物标志物研究 生物标志物研究
背景情况:
- D-二聚合物是凝血激活和纤维素分解的关键生物标志物.
- 它经常用于诊断和管理静脉血栓塞栓症 (VTE).
- 升高的D-二聚物水平也可能是由于衰老,怀孕和各种疾病等非血栓性疾病造成的.
研究的目的:
- 提供关于在门诊患者中提高D-二次体水平的管理的叙述性综述.
- 为血液学家在评估和管理没有血栓形成的临床症状的D-二次体增加的个体的指导.
主要方法:
- 与D-dimer.相关的研究和临床指南的文献综述.
- 综合了关于差异诊断和高D-维度的管理策略的信息.
主要成果:
- D-二次元升高是常见的,可以由许多生理和病理条件引起.
- 区分VTE与其他引起D-二次元升高的原因需要仔细的临床评估.
- 管理策略应根据个体患者的临床背景量身定制.
结论:
- 血液学家经常遇到患有D-二次体升高而没有明显的血栓形成的患者.
- 需要采用系统的方法来区分VTE与D-二次数升高的其他原因.
- 这一审查为有效管理此类案件提供了一个框架.
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