在BNT162b2 Pfizer-BioNTech mRNA疫苗接种后青少年的心声功能评估:初步前性研究
Wan-Fu Hsu1,2, Chih-Hsiung Hsu3,4, Mei-Jy Jeng2,5,6
1Department of Pediatrics, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC.
Journal of the Chinese Medical Association : JCMA
|October 26, 2023
概括
接种COVID-19疫苗是非常重要的. 这项研究发现,在接种瑞-生物科技疫苗后,青少年的心脏功能没有显著变化,尽管有一些暂时的不适.
科学领域:
- 心脏病学 心脏病学
- 疫苗学 疫苗学 疫苗学
- 儿科 儿科 儿科
背景情况:
- 接种COVID-19疫苗对公共健康至关重要.
- 对于mRNA疫苗诱导的年轻男性心肌炎存在担忧.
- 青少年的潜在心声回声数据有限.
研究的目的:
- 在mRNACOVID-19疫苗接种后的青少年中前性评估心脏功能.
- 为了评估潜在的心脏副作用,使用串行心声回声学.
主要方法:
- 招募了25名接受BNT162b2疫苗的青少年 (12-15岁).
- 在基线和第2,7,14和28天进行了连续回声心电图.
- 在整个随访期间监测临床症状.
主要成果:
- 通过射出分数测量心脏功能,在所有参与者中保持稳定.
- 在接种疫苗后28天内没有发现任何显著的心脏异常.
- 72%的青少年报告过渡性,轻微的疫苗接种后不适,在28日消失.
结论:
- 青少年接种BNT162b2疫苗在28天内没有导致显著的心脏功能障碍.
- 过渡性不适是常见的,但在这个队列中没有观察到严重的心脏事件.
- 需要进一步的研究,以充分了解青少年的mRNA疫苗相关心肌炎.
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