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Murine Echocardiography of Left Atrium, Aorta, and Pulmonary Artery
Published on: February 20, 2017
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在肥胖患者中改善左心房扩大的识别
Yaar Aga1,2, Yalin Acardag1, Jie Fen Chin1,2
1Department of Cardiology, Franciscus Gasthuis & Vlietland, Kleiweg 500, Rotterdam, 3045 PM, The Netherlands.
The international journal of cardiovascular imaging
|October 26, 2023
概括
在肥胖患者中,以高度平方指数的左心房体积 (LAVh2) 是左心房功能障碍的更好的指标,而不是以身体表面积 (LAVBSA) 的指数. 在这个人群中,LAVh2更准确地识别了左心房功能下降.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
- 肥胖医学 肥胖医学
背景情况:
- 在肥胖患者中标准化左心房体积 (LAV) 是很困难的,因为身体组成的变化.
- 肥胖与心血管风险增加有关,包括潜在的左心房异常.
研究的目的:
- 研究中度至重度肥胖患者的左心房体积与高度平方 (LAVh2) 索引和左心房功能之间的关系.
- 为了比较LAVh2与LAV指数为身体表面积 (LAVBSA) 的诊断性能,以确定左心房功能障碍.
主要方法:
- 分析了142名中度至重度肥胖 (BMI ≥35 kg/m2) 的患者的心声图.
- 左心房体积被索引为高度平方 (LAVh2) 和身体表面积 (LAVBSA).
- 使用斑点跟踪回声心脏学来评估左心房功能,测量LA储应变 (LASr),LA导管应变 (LAScd) 和LA收缩应变 (LASct),其功能障碍定义为LASct<14%.
主要成果:
- 54.2%的患者有左心房扩大指数为高度平方 (LAEh2),而18.3%的患者有LAE指数为BSA (LAEBSA).
- 与没有LAEh2的人相比,LAEh2组的LA收缩菌株 (LASct) 显着较低 (12.2%±3.2%对13.6%±4.5%,p=0.019).
- LAEh2发现的LA功能障碍患者 (41.5%) 比LAEBSA (15.0%,p<0.001) 的患者显著多.
结论:
- 索引左心房体积与高度平方 (LAVh2) 优于索引身体表面积 (LAVBSA),用于检测肥胖个体的左心房功能障碍.
- 在中度至重度肥胖患者中,LAVh2应该是LAV标准化的首选方法,以更好地评估心脏健康.
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