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在例行CMR检查的人群中,每种病理的正常化肺过渡时间的分布
A Jossart1, B Gerber2, L Houard3
1Division of Cardiology, Cliniques Universitaires Saint-Luc, Bruxelles, Belgium. adrienjossart@gmail.com.
The international journal of cardiovascular imaging
|October 26, 2023
概括
通过心脏磁共振 (CMR) 测量的肺过渡时间 (PTT) 是心脏病理学的有价值指标. 这项研究发现,正常化的PTT (nPTT) 根据性别和疾病类型而异,突出显示了它在评估心脏病的作用.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
- 生理学 生理学 生理学
背景情况:
- 肺过渡时间 (PTT) 非侵入性评估预负载,反映右心室到左心室对比剂过渡.
- 在各种成像方式中使用PTT,包括心声学和心磁共振 (CMR).
- 最近的研究强调了PTT的预后意义,促使进一步调查.
研究的目的:
- 为了评估经历CMR的连续患者队列中正常化肺传输时间 (nPTT),
- 确定nPTT与人口因素 (性别) 和心脏病理之间的关系.
- 评估nPTT与左心室体积和喷射分数的相关性.
主要方法:
- 在2017年8月至2021年11月期间接受CMR的278名患者的回顾性分析.
- 计算心率正常化的PTT (nPTT) 患者的诊断包括扩张性心肌病,心脏病发作,高,膜疾病,心肌炎,和一个"正常"的组.
- 统计分析比较不同组的nPTT,并将其与心脏参数相关联.
主要成果:
- 在"正常"组的男性中,正常化的PTT (nPTT) 显著高于女性 (8.4±1.3比7.5±1.1节拍,p=0.002).
- nPTT与左心室末端透缩体积 (r2=0.19),左心室末端透缩体积 (r2=0.34),和左心室喷射率 (r2=0.29) 有中等相关性.
- 与"正常"组 (7.9±1.3节拍) 相比,患有扩张性心肌病 (11.3±5.4节拍),心脏病发作 (9.5±2.9节拍) 或膜心脏病 (9.5±3.1节拍) 的患者的nPTT显著更高.
结论:
- 正常化肺传输时间 (nPTT) 是心脏病理学的重要指标.
- nPTT的值受患者的性别和特定类型的心脏病理的影响.
- 虽然nPTT是一种有价值的标志物,但它缺乏针对个体病理的特异性,因此需要在临床背景下进行解释.
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