相关实验视频
Updated: Jul 12, 2025

Optimized Analysis of In Vivo and In Vitro Hepatic Steatosis
Published on: March 11, 2017
脂肪肝疾病:进入新陈代谢时代
Kara Wegermann1, Cynthia Moylan1,2, Susanna Naggie3,4
1Division of Gastroenterology, Department of Medicine, Duke University Health System, Durham, NC, USA.
与代谢功能障碍相关的脂肪性肝病 (MASLD) 影响了近一半的艾滋病毒感染者 (PWH). 在这种高风险人群中,早期查和干预对于管理MASLD至关重要.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 传染性疾病 传染性疾病
- 代谢障碍 代谢障碍 代谢障碍
背景情况:
- 与代谢功能障碍相关的脂肪性肝病 (MASLD) 是一个日益严重的全球健康问题.
- 艾滋病毒感染者 (PWH) 代表了一种具有高代谢并发症负担的人群.
- 了解艾滋病毒和MASLD的交叉关系对于患者的治疗结果至关重要.
研究的目的:
- 审查当前关于艾滋病毒感染和MASLD之间的关联的文献.
- 突出MASLD在PWH中的流行率和促成因素.
- 强调需要在PWH中制定MASLD的预防和治疗策略.
主要方法:
- 最近研究的文献综述.
- 对一般人群和PWH中MASLD导致的因素的分析.
- 检查HIV特异性因素的影响,包括抗逆转录病毒疗法 (ART).
主要成果:
- 在PWH中,MASLD的患病率很大,可能达到50%.
- 在PWH中MASLD是多因素的,受代谢综合征,全身炎症和ART的影响.
- 类固醇治疗在减少PWH心血管事件方面显示出好处.
结论:
- 在PWH中,患MASLD的风险较高.
- 查具有代谢综合征特征的PWH可以促进早期干预.
- 在PWH中及时管理MASLD至关重要,以减少相关的发病率和死亡率.
更多相关视频
08:41Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease
Published on: March 24, 2023
07:03Author Spotlight: Establishing MASLD Cell Models for Investigating Disease Mechanisms and the Lipid-Lowering Effects of Koumiss
Published on: July 19, 2024
相关概念视频
Overview of Fatty Acid Metabolism
Fatty acids are catabolized in a process called beta-oxidation, which takes place in the matrix of the mitochondria and converts their fatty acid chains into two-carbon units of acetyl groups. The acetyl...
Overview of Lipid Metabolism
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
Ultrasound II: Endoscopic Ultrasound and FibroScan
Endoscopic Ultrasound (EUS):
Liver Physiology
Metabolic Regulation:
The liver is the central organ involved in regulating blood composition. It stabilizes blood glucose levels, maintaining them within the range of 70–110 mg/dL. When these levels drop, the liver breaks down glycogen reserves and releases glucose into the bloodstream. It can...
Lipid Catabolism
Regulation of Metabolism