风险中风,心肌梗塞,死后视网膜动脉堵塞视网膜动脉堵塞
Karen M Wai1, Austen Knapp1, Cassie A Ludwig1
1Byers Eye Institute, Horngren Family Vitreoretinal Center, Department of Ophthalmology, Stanford University School of Medicine, Palo Alto, California.
JAMA ophthalmology
|October 26, 2023
概括
与白内障患者相比,视网膜动脉封闭 (RAO) 的患者在短期和长期内面临的死亡,中风和心肌梗塞 (MI) 风险明显更高. 这强调了需要全面的,长期的患者监测.
科学领域:
- 眼科医生 眼科 眼科
- 心脏病学 心脏病学
- 神经学 神经学
背景情况:
- 视网膜动脉封闭 (RAO) 需要突发性中风治疗,但相关的死亡风险和随后的血管事件仍然不清楚.
- 了解这些风险对于患者的管理和预后至关重要.
研究的目的:
- 评估和比较RAO后患者中风,心肌梗塞 (MI) 和死亡的短期和长期发病率,与匹配的对照组相比.
主要方法:
- 一个回顾性队列研究,利用TrinetX电子健康记录从超过1.11亿患者 (2003-2023).
- 诊断为RAO的患者与基于年龄,性别,种族和并发症的诊断为白内障的对照组相匹配.
- 排除标准包括先前的中风或在诊断后两年内发生的MI.
主要成果:
- 与对照人群相比,RAO患者在诊断后2周,30天,1年,5年和10年的死亡率显着更高.
- 在所有测量间隔 (2周至10年) 中,RAO队列中,中风风险大幅增加.
- 同样,在所有测量时间点上,RAO患者心肌梗塞 (MI) 的风险更高.
结论:
- 患有RAO的患者有死亡,中风和心脏病发作的风险增加,从短期到长期随访持续.
- 这些发现强调了多学科评估和对RAO后个人持续系统监测的必要性.
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