支付人和开发人员对替代支付模式的看法
Renita Moradian1, Tsega Meshesha1, Mark Trusheim1
1New Drug Development Paradigms (NEWDIGS) Initiative, Center for Biomedical System Design, Tufts Medical Center Institute for Clinical Research and Health Policy Studies, Boston, MA, USA.
Expert review of pharmacoeconomics & outcomes research
|October 26, 2023
概括
大多数美国细胞和基因疗法 (CGT) 开发商和支付人正在使用或计划使用替代支付模式. 关键的动机包括管理成本和改善患者接入,尽管存在管理和绩效测量方面的挑战.
科学领域:
- 卫生经济学与研究成果研究成果
- 制药政策和管理 制药政策和管理
- 生物技术和治疗学
背景情况:
- 细胞和基因疗法 (CGT) 在美国市场提出了独特的报销挑战.
- 与CGT相关的高成本和不确定性需要创新的支付解决方案.
- 了解开发商和付款人的观点对于成功的退款策略至关重要.
研究的目的:
- 调查美国CGT替代支付模式 (APM) 的采用和动机.
- 确定在CGT补偿中实施APM的感知障碍和促进者.
- 探索现实世界的证据在裁决APM合同中的作用.
主要方法:
- 进行了文献搜索,以告知关于CGT补偿的调查发展.
- 在2022年6月至8月期间,向美国CGT开发商 (n=100) 和付款人 (n=195) 分发了一项在线调查.
- 对调查答案的分析,以确定APM实施的趋势,动机和障碍.
主要成果:
- 大多数开发者 (81%) 和支付者 (84%) 已经实施或计划实施APM.
- 付款人利用APM来缓解业绩和精算不确定性,而开发者则旨在简化患者的访问和预算影响.
- 常见的障碍包括行政负担,定义绩效指标和患者流动性;注意到愿意使用现实世界的证据.
结论:
- 早期讨论和对动机的相互理解对于创建有效的CGT合同至关重要.
- APM正在成为解决CGT补偿障碍的关键策略.
- 需要进一步的研究,考虑到研究的参与者限制,以完善CGT的APM框架.
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