增加的同情刺激会减缓运动后心率恢复的速度
Natasha G Boyes1, Joseph Mannozzi2, Nicole Rapin1
1College of Kinesiology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Journal of applied physiology (Bethesda, Md. : 1985)
|October 26, 2023
概括
从肌肉代谢反射激活 (MMA) 持续的交友刺激减缓了运动后心率恢复. 通过降低烯 (PE) 减少同情激发,使这种恢复部分正常化,这表明MMA.
科学领域:
- 运动生理学 运动生理学
- 自主神经系统功能 自主神经系统功能
- 心血管监管 监管心血管系统
背景情况:
- 运动后心率恢复缓慢与持续的同情兴奋有关.
- 肌肉代谢反射 (MMA) 是这种同情激发的潜在贡献者.
- 了解MMA的作用对于确定心血管恢复受损的机制至关重要.
研究的目的:
- 为了研究MMA对动态运动后心率恢复的影响.
- 为了确定通过烯 (PE) 激活巴罗反射能否逆转MMA对犬类心率恢复的影响.
主要方法:
- 人类参与者 (n=22) 和有仪器的狗 (n=5) 接受了循环人体力测量和适度运动协议.
- 肌肉代谢反射激活 (MMA) 是通过减少后肢血流来诱导的.
- 测量了心率恢复动力学,平均动脉压 (MAP) 和心率变化 (RMSSD).
- 用烯 (PE) 输液来激活巴罗反射并降低犬类的同情激发.
主要成果:
- 在人类和犬类中,MMA显著减缓了心率恢复.
- 在早期康复期间,MMA增加了MAP并减少了心率变化 (RMSSD).
- 在MMA期间给狗注入烯 (PE) 加快了心率的恢复,使其恢复到控制水平.
- 运动结束/恢复心率的幅度和心率在各个条件之间没有显著差异.
结论:
- 肌肉代谢反射激活诱导的交感兴奋会影响运动后心率恢复.
- 降低的副交感活动与MMA期间心率恢复速度较慢相关.
- 通过PE的药理学交感抑制在MMA期间部分正常化心率恢复,突出了交感兴奋的作用.
更多相关视频
07:40Impact of High-intensity Interval Exercise and Moderate-Intensity Continuous Exercise on the Cardiac Troponin T Level at an Early Stage of Training
Published on: October 10, 2019
7.3K
12:45Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
Published on: December 11, 2017
10.5K
相关概念视频
01:20Exercise and Cardiovascular Response
834
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
834
01:17Sympathetic Activation
5.3K
The sympathetic division can influence tissues and organs by releasing norepinephrine at peripheral synapses and distributing epinephrine and norepinephrine through the bloodstream. In times of crisis or stress, sympathetic activation occurs, which is regulated by sympathetic centers in the hypothalamus. As a result, sympathetic activation prepares the body for physical exertion, rapid ATP production, and heightened alertness, allowing individuals to respond effectively to challenging or...
5.3K
01:31Regulation of Heart Rates
1.8K
The regulation of heart rate is a complex process controlled by the autonomic nervous system (ANS), hormonal influences, and intrinsic cardiac mechanisms. The ANS has two main components: the sympathetic nervous system (SNS) and the parasympathetic nervous system (PNS).
The SNS increases heart rate through the release of norepinephrine and epinephrine, which act on beta-1 adrenergic receptors in the heart. This action increases the rate of depolarization in the sinoatrial (SA) node, the heart's...
The SNS increases heart rate through the release of norepinephrine and epinephrine, which act on beta-1 adrenergic receptors in the heart. This action increases the rate of depolarization in the sinoatrial (SA) node, the heart's...
1.8K
01:30Factors Influencing Heart Rate
2.7K
The heart rate, or pulse rate, is a vital indicator of cardiovascular health. It reflects the number of times the heart beats per minute. Various physiological and environmental factors influence heart rate, increasing or decreasing cardiac output. Understanding these factors is crucial for assessing heart function and identifying potential health issues.
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
2.7K
01:29Heart Failure II: Pathophysiology
14
Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
14
01:26Heart Failure Drugs: Inhibitors of Renin-Angiotensin System
438
The activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS) contributes to cardiac remodeling, and inhibiting the RAAS is a pharmacological target in heart failure management. As a result, neurohumoral modulation is a crucial treatment principle for managing heart failure. This approach involves using medications like ACE inhibitors (ACEIs), angiotensin receptor blockers (ARBs), β-blockers, mineralocorticoid receptor antagonists (MRAs), and neutral...
438