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Updated: Jul 12, 2025

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病毒编码的互白素-6促进KSHV在单细胞中的复制,并诱导功能失调的巨细胞

Michiko Shimoda1,2, Tomoki Inagaki1, Ryan R Davis3

  • 1Department of Dermatology, School of Medicine, University of California, Davis, Sacramento, California, United States of America.

PLoS pathogens
|October 26, 2023
PubMed
概括

卡波西的肉瘤相关性疹病毒 (KSHV) 使用病毒性互白素-6 (vIL-6) 来扩大受感染的单细胞到功能失调的巨细胞,帮助病毒的持久性. 这种机制有助于KSHV逃避免疫监测,并建立终身感染.

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