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Exogenous Administration of Microsomes-associated Alpha-synuclein Aggregates to Primary Neurons As a Powerful Cell Model of Fibrils Formation
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Published on: June 26, 2018

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中性lysophosphatidylcholine介导α-synuclein诱导的突触囊泡聚类

Ying Lai1,2, Chunyu Zhao3, Zhiqi Tian4

  • 1National Clinical Research Center for Geriatrics, West China Hospital, State Key Laboratory of Biotherapy and Collaborative Innovation Center of Biotherapy, Sichuan University, Chengdu, Sichuan 610065, China.

Proceedings of the National Academy of Sciences of the United States of America
|October 26, 2023
PubMed
概括

阿尔法-同核素 (α-Syn) 与中性溶解酸丁胆 (lysoPC) 相互作用,促进囊泡集群,独立于离子脂质. 这种相互作用对α-Syn至关重要.

关键词:
斯纳雷 (Snare) 是一个小鸟.膜膜膜膜是一种单个分子单个分子.突触囊泡中的突触囊泡.α-synuclein 是一种同核蛋白.

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