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宫外妊娠的全球负担和趋势:从1990年到2019年的观察趋势研究
Shufei Zhang1, Jianfeng Liu1, Lian Yang1
1Department of Obstetrics and Gynecology, Renmin Hospital of Wuhan University, Wuhan, Hubei Province, P.R.C.
PloS one
|October 26, 2023
概括
异胎妊娠 (EP) 的发病率和死亡率在过去30年中在全球范围内有所下降,但不利地区的上升趋势凸显了对弱势妇女有针对性的支持的需要. 这项研究分析了1990-2019年全球EP数据.
科学领域:
- 生殖健康 生殖健康
- 流行病学 流行病学
- 全球健康 全球健康
背景情况:
- 宫外怀孕 (EP) 仍然是早期怀孕死亡的重要原因.
- 虽然发达国家死亡率有所下降,但最近的流行病学数据很少.
- 这项研究通过分析30年的数据集来解决这个差距.
研究的目的:
- 分析异胎妊娠发病率,死亡率和疾病负担的全球趋势.
- 调查子宫外妊娠指标与社会人口因素之间的相关性.
- 识别风险因素并为公共卫生战略提供信息.
主要方法:
- 利用了1990-2019年全球疾病负担 (GBD) 数据.
- 雇员估计年均百分比变化 (EAPC) 评估年龄标准化利率的趋势.
- 分析了与社会人口统计指数 (SDI) 和年龄分层的相关性.
主要成果:
- 2019年,EP的全球年龄标准化发病率 (ASIR) 为170.33/100,000人.
- 全球年龄标准化死亡率 (ASDR) 为0.16/100,000人,与SDI负相关 (R = -0.699).
- 铁缺乏被确定为危险因素;ASDR和AS-DALY显示了类似的模式.
结论:
- 异胎妊娠的发病率,死亡率和负担在过去的30年里有所下降.
- 在经济上处于劣势的地区显示出日益增长的趋势,需要有针对性的干预措施.
- 加强对少数民族和低收入妇女的支持至关重要.
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