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Updated: Jul 12, 2025

Author Spotlight: Characterizing Novel Enzymes from Extremophiles and Common Pathogens to Understand DNA Repair and Replication
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Author Spotlight: Characterizing Novel Enzymes from Extremophiles and Common Pathogens to Understand DNA Repair and Replication

Published on: July 5, 2024

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三价稀土金属共因子赋予快速的NP-DNA聚合酶活性

Victor S Lelyveld1,2, Ziyuan Fang1,2,3, Jack W Szostak1,2,3,4,5,6

  • 1Center for Computational and Integrative Biology, Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA.

Science (New York, N.Y.)
|October 26, 2023
PubMed
概括

研究人员通过识别优异的金属离子辅因子,增强了非自然的N3'→P5'胺酸 (NP) DNA合成. 与标准的 (II) 辅因子相比, (III) 显著增加了NP-DNA的形成.

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