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Updated: Jul 12, 2025

Hybrid De Novo Genome Assembly for the Generation of Complete Genomes of Urinary Bacteria using Short- and Long-read Sequencing Technologies
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Hybrid De Novo Genome Assembly for the Generation of Complete Genomes of Urinary Bacteria using Short- and Long-read Sequencing Technologies

Published on: August 20, 2021

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合并短读和长读,改进了转录组装

Amoldeep S Kainth1, Gabriela A Haddad2, Johnathon M Hall1

  • 1Department of Molecular Genetics and Cell Biology, The University of Chicago, Chicago, Illinois, United States of America.

PLoS computational biology
|October 26, 2023
PubMed
概括

这项研究引入了一种新的混合测序方法,以准确地组装长非编码RNA (lncRNA) 转录. 我们的方法克服了短读和长读测序的局限性,改善了转录末端和异形结构分析.

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