剪切力诱导的血小板清除是血小板缺血的一个新机制

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Updated: Jul 12, 2025

A Uniform Shear Assay for Human Platelet and Cell Surface Receptors via Cone-plate Viscometry
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A Uniform Shear Assay for Human Platelet and Cell Surface Receptors via Cone-plate Viscometry

Published on: June 5, 2019

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Antoine Rauch1,2, Annabelle Dupont1,2, Mickael Rosa1,2

  • 1Inserm, Institut Pasteur de Lille, France (A.R., A.D., M.R., M. Desvages, C.L.T., J.A., M. Didelot, A.U., R.R., E.J., M. Daniel, D.C., H.S., B.P., N.R., M.D.M., A.V., B.S., F.V., E.V.B., S.S.), CHU Lille, University Lille, France.

Circulation research
|October 26, 2023
PubMed
概括

身体外膜氧化 (ECMO) 通过诱导糖蛋白Iba (GP Ibα) 因剪切力而脱落而导致血小板缺血. 这导致GP Ibα阴性血小板的清除速度更快,这表明抑制脱落可以减少ECMO期间的低血小板数量.

关键词:
血小板是血液中的血小板.身体外膜氧化氧化发生出血 发生出血血小板计数 血小板计数 血小板计数 血小板计数血小板细胞减少症 (Thrombocytopenia) 是一种

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