在心脏移植中增加捐赠心脏的使用
Stephen A DeVries1, Jason Smith
1Stephen A. DeVries practices in cardiothoracic surgery at Vanderbilt University Medical Center in Nashville, Tenn. Jason W. Smith is a cardiothoracic surgeon and director of heart transplantation and mechanical circulatory support at the University of California-San Francisco. The authors have disclosed no potential conflicts of interest, financial or otherwise.
概括
供体心脏短缺会加剧移植等待时间和死亡率. 扩大捐赠心脏的标准,包括扩大标准,增加风险,型肝炎和循环死亡捐赠者的捐赠,可以增加器官的可用性.
科学领域:
- 心脏病学和移植外科手术
背景情况:
- 供体心脏的严重短缺显著影响心脏移植的结果.
- 更长的等待时间和增加的死亡率是捐赠者心脏缺陷的直接后果.
- 预计可用捐赠器官和需要心脏移植的患者之间的差距将会扩大.
研究的目的:
- 为了解决心脏移植供体心脏的严重短缺问题.
- 探索扩大捐赠心脏池的策略.
主要方法:
- 审查当前的做法和增加捐赠心脏的潜在来源.
- 从扩展标准捐赠者器官利用率的分析.
- 考虑来自公共卫生服务的器官增加了风险,型肝炎阳性,以及在循环死亡后的捐赠者.
主要成果:
- 捐赠者心脏池有限,导致满足患者需求的重大挑战.
- 使用来自扩大标准捐赠者的器官是一个可行的选择,以增加可用性.
- 循环死亡和型肝炎阳性捐赠者后的捐赠代表了未充分利用的资源.
结论:
- 扩大供体心脏的标准对于减轻短缺至关重要.
- 纳入来自不同类型的捐赠者的器官,包括扩展的标准和循环死亡后的捐赠,可以改善移植的可访问性.
- 解决捐赠心脏短缺问题需要对器官采购和利用采取多方面的方法.
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