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Updated: Jul 12, 2025

Comprehensive Evaluation of the Effectiveness and Safety of Placenta-Targeted Drug Delivery Using Three Complementary Methods
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简要报告:多卢特格拉维尔血蛋白结合和未结合度在怀孕和产后期间

Jeremiah D Momper1, Mina Nikanjam2, Brookie M Best1,2

  • 1Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA.

Journal of acquired immune deficiency syndromes (1999)
|October 26, 2023
PubMed
概括

怀孕减少了多卢特格拉维尔 (DTG) 蛋白质的结合,导致第三个三个月和产后的DTG未结合水平相似. 这一发现对于了解艾滋病毒感染孕妇的DTG药理动力学至关重要.

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