弥合差距:对报告基线特征,过程和结果参数的系统性审查,直交状海尔施普朗格病
Daniel Rossi1,2,3, Anna Löf Granström2,4, Nadine M Teunissen1,3
1Department of Pediatric Surgery, Erasmus University Medical Centre - Sophia Children's Hospital, Rotterdam, The Netherlands.
概括
希尔施普朗格病的研究缺乏标准化的参数,阻碍了比较和质量评估. 本综述确定了共同的指标,并主张建立一个核心指标集,以改善数据解释和护理质量评估.
科学领域:
- 儿科手术 儿科手术
- 临床研究方法论 临床研究方法论
- 医疗保健服务研究 医疗服务研究
背景情况:
- 赫施普隆病 (HSCR) 研究中标准化参数的变化阻碍了跨机构的比较和质量评估.
- 最近的出版物显示HSCR的基线特征,过程措施和结果指标的利用和定义存在显著差异.
研究的目的:
- 为了解决在赫施普朗格病研究中报告的标准化参数的显著变异性.
- 编制HSCR文献中通常描述的基线特征,过程测量和结果测量的列表.
- 调查HSCR研究中的参数的利用和定义的差异.
主要方法:
- 系统的文献审查遵循PRISMA指南.
- 在2015年至2021年间发表的HSCR研究中搜索了Medline,Embase和Cochrane图书馆.
- 从200个出版物中提取并分类了1026个参数,分为患者特征,治疗/护理过程和结果.
主要成果:
- 在超过5%的出版物中报告了116个参数.
- 最常见的参数包括性别 (88%),手术时的年龄 (66%), postoperative Hirschsprung-associated enterocolitis (64%),修复类型 (57%),便失禁 (54%) 和腺瘤的程度 (51%).
- 在研究报告和参数定义方面存在显著差异.
结论:
- 报告参数的明显变化需要一致的,明确的措施来改善HSCR研究中的数据解释性.
- 倡导制定一个核心指标集,补充现有的核心成果集,以促进欧洲儿科外科中心的质量评估.
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