对转移性癌症患者进行以意义为中心的疼痛应对技能培训:随机对照疗效试验的协议
Hannah M Fisher1, Devon K Check2, Tamara J Somers1
1Pain Prevention and Treatment Research Program, Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA; Duke Cancer Institute, Duke University Health System, Durham, NC, USA.
Contemporary clinical trials
|October 26, 2023
概括
这项研究介绍了以意义为中心的疼痛应对技能培训 (MCPC),这是一种针对晚期癌症患者的新干预措施. 通过与传统的心理社会方法一起解决精神问题,MCPC旨在减少疼痛干扰并改善生活质量.
科学领域:
- 在瘤学瘤学.
- 心理社会干预 心理社会干预
- 疼痛管理 疼痛管理
背景情况:
- 晚期癌症疼痛显著影响日常生活和幸福感.
- 对于癌症疼痛的现有心理社会干预往往忽视了精神问题.
- 精神因素,如失去意义,可以加剧危及生命的疾病的痛苦经历.
研究的目的:
- 系统地开发和试点测试一种新的心理社会干预,即以意义为中心的痛苦应对技能培训 (MCPC).
- 确定MCPC在减少晚期癌症患者疼痛干扰 (主要结局) 的疗效.
- 评估MCPC对二次结果的影响,并估计其成本效益.
主要方法:
- 一项随机对照试验,涉及210名患有高级固体瘤恶性瘤 (第四阶段) 和高疼痛干扰的患者.
- 参与者将被随机分组为接受MCPC加上增强的常规护理或单独增强的常规护理.
- MCPC由每周四次45-60分钟的视频会议会议组成,由训练有素的治疗师单独进行. 在基线,8周和12周评估结果.
主要成果:
- 这项研究旨在评估MCPC在减少疼痛干扰方面的有效性.
- 二次结果包括疼痛严重程度,焦虑,抑郁症状,疼痛自我效能,社会支持和精神福祉.
- 疼痛干扰的主要终点是在干预后8周评估的.
结论:
- MCPC是第一个系统地解决癌症晚期疼痛的生物心理社会精神方面的干预措施.
- 如果有效,MCPC可以进一步发展,以实现更广泛的实施.
- 目标是通过可访问的,远程交付的干预措施来减少危及生命的疾病患者的痛苦.
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