在固体器官移植接受者的疹疹感染
Nuran Sarı1, Çiğdem Erol, Tuğba Yanık Yalçın
1From the Infectious Disease and Clinical Microbiology, Baskent University Faculty of Medicine, Ankara, Turkey.
概括
疹 (shingles) 感染对实体器官移植接受者是一个严重的风险. 早期治疗和预防性疫苗接种策略对于管理和预防这些感染及其并发症至关重要.
科学领域:
- 移植手术 移植手术
- 传染性疾病 传染性疾病
- 免疫学 免疫学 免疫学
背景情况:
- 固体器官移植接受者面临复杂且可能致命的疹感染的风险增加.
- 了解这种脆弱人群中疹的发病率,风险因素和临床表现对于患者管理至关重要.
研究的目的:
- 研究成年固体器官移植受体中疹感染的发病率和特征.
- 在脏,肝脏和心脏移植接受者中识别与疹相关的危险因素和临床结果.
主要方法:
- 从2011年1月到2022年6月,对1050名成年固体器官移植接受者的回顾性分析.
- 44名被诊断患有疹感染的患者的详细审查,包括移植类型,人口统计,临床表现和并发症.
主要成果:
- 疹的总发病率为5.2%,心脏 (9.7%) 和脏 (5.1%) 移植接受者的发病率更高.
- 在45岁以上的患者中,术后神经疼痛更为常见 (P = .006).
- 在心脏移植接受者中,神圣皮肤瘤的参与率显著高 (P = .015),而急性神经炎在移植接受者中更为频繁 (65.6%).
结论:
- 早期和特定的治疗,以及支持性护理,对于患有黄疹的移植受体至关重要.
- 建议在移植候选人中实施抗病毒预防和针对疹病毒 (VZV) 的疫苗接种策略,以预防感染和并发症.
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