[在免疫能力强的病例中带有血的Pasteurella multocida肺炎]
Işılay Gökçe Benk Uğur1, Elif Seren Tanrıverdi2, Mehmet Özgel3
1Turgut Özal University Faculty of Medicine, Department of Medical Microbiology, Malatya, Türkiye.
本病例报告详细介绍了一例罕见的帕斯图雷拉多种肺炎病例,该病例发生在患有支气管病的患者身上. 早期的微生物学评估和分子分类对于诊断P. multocida呼吸道感染至关重要.
科学领域:
- 医学微生物学 医学微生物学
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
背景情况:
- 在物植物中常见的帕斯图雷拉菌种,可在动物咬伤或划伤后引起人体感染,主要是皮肤和软组织.
- 呼吸道感染的巴斯图雷拉较少见,但可以发生在慢性肺部疾病或免疫力受损的个体中.
- 本报告重点介绍了一例罕见的P. multocida肺炎病例,该病例发生在患有支气管病的患者身上.
研究的目的:
- 在患有支气管病的患者中呈现一种罕见的由Pasteurella multocida引起的肺炎病例.
- 强调微生物学和分子诊断方法在呼吸道感染中识别P. multocida的重要性.
主要方法:
- 一名患有血栓塞,咳和体重减轻的患者接受了临床检查,胸部断层扫描和光纤支气管镜检查.
- 使用格拉姆染色,细菌培养,自动识别 (Vitek 2),抗生素图 (磁盘扩散) 和序列分析分析了支气管洗样本.
- 分子类型测定证实了该分离物与P. multocida.的同质性.
主要成果:
- 胸部断层扫描显示了左下叶的囊性结构和肺部透.
- 经过格拉姆染色和支气管洗培养,确定了格拉姆阴性可可球菌,随后通过序列分析确定为Pasteurella multocida (99.85%的同源性).
- 隔离物对几种抗生素敏感,包括勒沃克萨辛,三甲胺-硫甲醇和阿莫西西林-克拉夫兰酸.
结论:
- 虽然不常见,但P. multocida肺炎可能会发生,特别是在患有 bronchiectasis等先前存在的肺部疾病的患者中.
- 及时准确的诊断需要对风险患者的呼吸道样本进行彻底的微生物学评估,包括分子类型,以获得准确的诊断结果.
- 这一案例强调了在慢性呼吸系统疾病患者肺炎的差异诊断中考虑P. multocida的必要性.
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