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2型糖尿病患者住院的药物相关问题:系统性审查
Mohammad Hisyamuddin Awang Jihadi1, Ana Yuda2, Anila Impian Sukorini2
1Pengiran Anak Puteri Rashidah Sa'adatul Bolkiah Institute of Health Sciences, Universiti Brunei Darussalam, Gadong, Brunei Darussalam.
Exploratory research in clinical and social pharmacy
|October 27, 2023
概括
与药物相关的问题 (DRPs) 在2型糖尿病 (T2DM) 的住院患者中很常见,患病率差异很大. 识别和预防这些问题对于患者护理至关重要.
科学领域:
- 药理学 药理学是指药理学的学科.
- 临床药房 临床药房
- 内部医学 内部医学
背景情况:
- 2型糖尿病 (T2DM) 是一个日益严重的全球健康问题,患病率和死亡率不断增加.
- 与药物相关的问题 (DRPs) 显著影响T2DM患者,特别是那些患有并存疾病的患者.
研究的目的:
- 系统地审查和评估在被诊断为T2DM的住院患者中DRP的患病率和特征.
主要方法:
- 在五个主要的在线数据库 (PubMed,Scopus,Google Scholar,Web of Science,Cochrane Library) 进行了系统的文献审查,截至2022年6月.
- 包括的研究以英语或马来语出版,并使用Joanna Briggs Institute (JBI) 批判性评估工具进行评估.
主要成果:
- 从939个初始记录中确定了20项研究,符合纳入标准.
- 在包括的研究中,DRP的总体患病率从7%到94%不等.
- 常见的DRP包括药物相互作用 (DDI),药物不良反应 (ADR),治疗有效性问题和药物滥用. 抗糖尿病药物 (甲福明),抗高血压药物,抗血小板药物和抗生素经常涉及药物类别.
结论:
- 住院的T2DM患者经历了DRP的高发病率.
- 对DRP的危险因素包括并发症,药物的数量和多药.
- 通过强大的研究设计进行进一步的研究对于有效的DRP检测,减少和预防策略至关重要.
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