在印度哈里亚那州农村地区的2型糖尿病患者中评估骨矿物质密度:一个分析的横截面研究
Nitish Khandelwal1, Surbhi Rajauria2, Siddhesh Pandurang Kanjalkar3
1Department of Pathology, Military Hospital Ambala Cantt, Ambala, IND.
Cureus
|October 27, 2023
概括
2型糖尿病 (T2DM) 与印度农村成年人的骨矿物质密度 (BMD) 较低有关. 建议糖尿病患者进行早期骨质疏松症查,以预防骨折.
科学领域:
- 内分泌学 在内分泌学.
- 骨的新陈代谢 骨的新陈代谢
- 公共卫生 公共卫生
背景情况:
- 糖尿病是一种影响多个器官系统的全球流行病.
- 2型糖尿病 (T2DM) 和骨矿物质密度 (BMD) 之间的关联仍然存在争议,发展中国家的数据有限.
- 在糖尿病患者中早期发现低BMD对于预防骨损失和骨脆弱性骨折至关重要.
研究的目的:
- 调查T2DM对印度农村人口的BMD的影响.
- 为了比较印度哈里亚纳州糖尿病人和非糖尿病人之间的BMD.
主要方法:
- 这是一项涉及850名25-60岁参与者 (425名T2DM,425名对照) 的横截面研究.
- 量化超声波 (QUS) 用于测量骨的BMD.
- 分析了数据,比较糖尿病和非糖尿病组之间的骨质量.
主要成果:
- 与非糖尿病患者 (21.6 kg/m2) 相比,糖尿病患者的身体质量指数 (BMI) (27.8 kg/m2) 显著更高.
- 两组之间观察到 BMD 的统计学上显著差异 (p=0.002),糖尿病患者的 BMD (-4.3 ± 1.23) 与非糖尿病患者 (-2.6 ± 0.34) 相比较低.
结论:
- 在被研究的印度农村人口中,T2DM与明显减少的骨硬化有关.
- 建议对所有T2DM患者进行例行骨质疏松症查,以便早期检测和干预无声骨质损失.
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