一种用于预测宫围患者预后的诺莫图
Jiaqi Xu1, Tianru Yang1, Fei Wu1
1Department of Obstetrics and Gynecology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, Jiangsu, 215002, China.
Heliyon
|October 27, 2023
概括
这项研究开发了用于接受 cerclage 的宫衰竭患者的预测性名录. 该工具有助于临床医生个性化治疗,改善早产风险的结果.
科学领域:
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 生殖医学 生殖医学
- 产科 产科 产科 产科 产科
背景情况:
- 宫衰竭增加了中期流产和早产的风险.
- 有效的管理策略对于改善胎儿结果至关重要.
- 对于宫功能不全的患者,需要个性化治疗方法.
研究的目的:
- 为在宫 cerclage 后出现宫衰竭的患者构建一个预测性 nomogram.
- 协助临床医生提供个性化治疗计划.
- 为了改善风险患者怀孕结果的预测.
主要方法:
- 从2013年1月到2022年7月,对211名患者进行了回顾性研究.
- 使用多变量考克斯回归分析和卡普兰-梅尔曲线.
- 使用R中的"rms"包开发了一个nomogram,使用开发和验证队列.
主要成果:
- 影响怀孕持续时间的关键因素包括妊娠时间,流产史,试管婴儿,腹痛和诊断分类.
- 诺米图表表现出令人满意的预测准确性,C指数为0.662 (发展) 和0.687 (验证).
- 临床决策曲线表明,对各种妊娠周的结果具有良好的预测效用.
结论:
- 开发的诺莫图谱是评估宫衰竭后宫衰竭患者的治疗结果的宝贵工具.
- 它支持临床医生量身定制个性化管理策略.
- 这有助于优化护理,并可能减少胎儿损失.
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