Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Lineage Commitment01:21

Lineage Commitment

3.0K
Commitment is the  process whereby stem cells:
3.0K
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

341
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
341

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Comprehensive lincRNA Transcriptome in Acute Myeloid Leukemia: Integrating Known and Newly Identified lincRNAs Across Pediatric and Adult Cohorts.

Non-coding RNA·2026
Same author

Sustained PRC1.1 activity preserves gene repression independently of PRC2.2 and restrains leukemic cell differentiation.

Nucleic acids research·2026
Same author

Identification of a robust metabolic signature associated with hospital-acquired pneumonia and response to interferon-gamma treatment in critically ill patients.

Critical care (London, England)·2026
Same author

Persistent viral control status is associated with enhanced innate immune responses in people with HIV-1.

iScience·2026
Same author

Phenotypic and epigenetic profiles of circulating NK cells in spontaneous HIV-1 controllers.

EBioMedicine·2025
Same author

Long-term effects of BCG vaccination on telomere length and telomerase activity.

iScience·2025

相关实验视频

Updated: Jul 12, 2025

Characterizing Mutational Load and Clonal Composition of Human Blood
07:58

Characterizing Mutational Load and Clonal Composition of Human Blood

Published on: July 11, 2019

7.4K

使用基于测序的技术和人类细胞系统了解血液发育和白血病.

Branco M H Heuts1, Joost H A Martens1

  • 1Department of Molecular Biology, Faculty of Science, Radboud University, Nijmegen, Netherlands.

Frontiers in molecular biosciences
|October 27, 2023
PubMed
概括

技术的进步正在彻底改变人类血液形成或血细胞生产的研究. 新的方法帮助研究人员了解血液疾病,并使精准医学成为可能.

科学领域:

  • 血液学 血液学 血液学
  • 分子生物学分子生物学
  • 基因组学就是基因组学.

背景情况:

  • 人类血液形成的理解正在不断发展,挑战传统观点.
  • 高通量技术产生各种数据,用于研究血细胞生产和疾病.
  • 正常和异常血液形成中的关键调节过程需要更深入的研究.

研究的目的:

  • 探索技术进步如何解开血液形成的分子机制.
  • 突出加强监管网络和转录监管的作用.
  • 讨论单细胞方法的潜力,体外分化系统,以及精准医学的患者概况.

主要方法:

  • 关于高通量技术和它们在血液形成中的应用的当前文献的审查.
  • 专注于增强剂相关的监管网络和增强剂衍生转录.
  • 讨论单细胞技术和诱导多能干细胞 (iPSC) 模型用于体外分化.
  • 探索用于精准医学的先进患者概况.

主要成果:

  • 技术进步为研究血液细胞生产提供了新的途径.
  • 增强调节网络和转录在造血过程中起着至关重要的作用.
  • 单细胞方法和iPSC模型为剖析造血过程提供了强大的工具.
关键词:
大数据就是大数据.我们的 eRNA eRNA.功能性基因组学 功能性基因组学基因监管网络 基因监管网络血液形成 血液形成这就是 iPSC 的意义.一个单细胞测序.转录因子是一种转录因子.

更多相关视频

Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up
09:01

Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up

Published on: March 26, 2018

14.0K
Author Spotlight: Analyzing Bone Marrow Microenvironment in Murine Hematological Malignancies
06:33

Author Spotlight: Analyzing Bone Marrow Microenvironment in Murine Hematological Malignancies

Published on: November 10, 2023

1.2K

相关实验视频

Last Updated: Jul 12, 2025

Characterizing Mutational Load and Clonal Composition of Human Blood
07:58

Characterizing Mutational Load and Clonal Composition of Human Blood

Published on: July 11, 2019

7.4K
Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up
09:01

Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up

Published on: March 26, 2018

14.0K
Author Spotlight: Analyzing Bone Marrow Microenvironment in Murine Hematological Malignancies
06:33

Author Spotlight: Analyzing Bone Marrow Microenvironment in Murine Hematological Malignancies

Published on: November 10, 2023

1.2K
  • 有细微差别的患者分析有助于准确医学方法.

    • 结论:

    • 建议采用基于监管网络的多参数方法,以全面理解血液形成.
    • 整合不同的数据类型和方法对于推进该领域至关重要.
    • 未来的研究应该利用这些工具来更好地理解和治疗血液疾病.