印度献血者中TTI的流行率
Sanjay Kumar Thakur1,2, Sompal Singh2, Dinesh Kumar Negi2
1P.G. Department of Zoology, Veer Kunwar Singh University, Ara, Bihar, India - 802301.
Bioinformation
|October 27, 2023
概括
输血传染性感染 (TTIs) 如HIV,HBV,HCV和梅毒是献血中的风险. 这项研究发现,德里献血者中TTI的患病率很低,梅毒和HCV与ABO血型有关.
科学领域:
- 医学微生物学 医学微生物学
- 公共卫生 公共卫生
- 血液学 血液学 血液学
背景情况:
- 输血传染性感染 (TTIs) 通过输血构成重大风险.
- 关键的TTIs包括人类免疫缺陷病毒 (HIV),乙型肝炎病毒 (HBV),乙型肝炎病毒 (HCV),疟疾寄生虫 (MP) 和梅毒.
研究的目的:
- 分析德里的献血者中TTI的流行情况.
- 调查TTI与血型 (ABO和Rh) 之间的关联.
主要方法:
- 德里的献血者使用ELISA (HIV,HBV,HCV),RPR (梅毒) 和快速卡方法 (MP) 进行TTI查.
- 血液分组是使用凝卡进行的.
- 使用统计分析来确定TTI和血型之间的关联.
主要成果:
- 总共有2.038%的献血者检测出TTIs的阳性.
- 患病率包括:HBV (1.111%),HCV (0.431%),HIV-I/II (0.201%),梅毒 (0.29%),MP (0.006%),这些病例的流行率均为以下几种.
- 在梅毒和HCV感染与ABO血型之间发现了显著的关联 (分别P=0.036和P=0.012).
- 血液组O的献血者患梅毒的风险更高,血液组B的献血者患HCV的风险更高.
- 在HBV/HIV流行率和ABO/Rh血型之间没有发现显著的关联.
结论:
- 在德里献血者中观察到TTI的发病率较低,从2020年至2022年间的趋势下降.
- ABO血型与梅毒和HCV感染有显著的关联.
- 公共意识,咨询和严格的查对于尽量减少献血中TTIs至关重要.
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