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Updated: Jul 12, 2025

Generating De Novo Antigen-specific Human T Cell Receptors by Retroviral Transduction of Centric Hemichain
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在血液和胰腺之间共享的自我反应的生殖系类似的TCRα链

Peter Linsley1, Maki Nakayama2, Elisa Balmas3

  • 1Benaroya Research Institute at Virginia Mason.

Research square
|October 27, 2023
PubMed
概括

血液中的人类小岛抗原反应性CD4+T细胞 (IAR T细胞) 透到胰腺,导致1型糖尿病 (T1D) 的进展. 共享的T细胞受体序列将血液IAR T细胞与T1D中的胰腺T细胞联系起来.

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