抑郁和焦虑症状与耐药患者的认知功能和生活质量之间的关联
E Monteagudo-Gimeno1,2, R Sánchez-González3,4, J Raduà-Castaño5,6,7,8,9
1Department of Psychiatry and Forensic Medicine, School of Medicine, Universitat Autònoma de Barcelona, Bellaterra, Cerdanyola del Vallès, Spain.
Heliyon
|October 27, 2023
概括
抑郁症和焦虑症在耐药性 (DRE) 中很常见,影响生活质量. 虽然焦虑/抑郁分数与生活质量相关,但它们与DRE认知功能的直接联系尚不清楚,需要进一步研究.
科学领域:
- 神经学 神经学
- 精神病学是一个精神病学.
- 认知科学 认知科学
背景情况:
- 抑郁和焦虑障碍,以及认知障碍,是的常见并发症.
- 这些并发症在耐药性 (DRE) 患者中具有更有害的影响.
- 在DRE中焦虑,抑郁和认知表现之间的特定关系的研究是有限的.
研究的目的:
- 为了研究焦虑和抑郁症状之间的关联和DRE患者的认知表现.
- 探索这些并发症对DRE患者生活质量 (QOL) 的影响.
主要方法:
- 使用医院焦虑和抑郁量表 (HADS) 和症状检查清单-90-修订 (SCL-90R) 来测量焦虑和抑郁症状.
- 使用标准化神经心理测试评估认知表现.
- 使用症生命质量清单 (QOLIE-31) 评估生活质量.
主要成果:
- 较高的HADS得分与较低的QOLIE-31得分有显著的关联,这表明HADS得分可能预测DRE中的QOL.
- 在焦虑和抑郁症状 (通过HADS和SCL-90R测量) 和认知表现之间没有发现显著的关系.
- 这项研究强调了理解情绪,认知和之间的复杂相互作用的差距.
结论:
- 焦虑和抑郁严重影响药物耐药性患者的生活质量.
- 目前的研究结果表明,焦虑和抑郁症状虽然影响了质量生活,但可能与DRE的认知缺陷没有直接相关.
- 需要进一步的研究来阐明这些关系,并改善DRE中全面的患者评估和管理.
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