用内镜超声波指导的胃水出血的初级和二级预防方法的比较
Yara Sarkis1, Howard Masuoka1, Marwan Ghabril1
1Department of Gastroenterology and Hepatology, Indiana University Health Medical Center, Indianapolis, USA.
概括
以内超声 (EUS) 指导的烯酸盐 (CYA) 注射用于胃静脉 (GV) 的初级预防,其安全性和有效性与二次预防相似. 这种EUS技术是防止GV出血的可行选择.
科学领域:
- 胃肠病学 胃肠病学
- 干预性内镜检查是干预性的内镜检查.
- 肝病学 肝病学是一种肝病学.
背景情况:
- 胃静脉 (GV) 具有显著的出血风险.
- 用内镜超声波 (EUS) 指导的烯酸 (CYA) 注射是对GV的治疗选择.
- 关于CYA对GV初级预防 (PP) 的有效性和安全性仍在争论中.
研究的目的:
- 评估EUS指导的CYA注射的安全性和有效性,用于胃 (GV) 的初级预防 (PP).
- 为了比较PP与GV患者的二次预防 (SP) 的结果.
主要方法:
- 针对GV的PP或SP进行EUS引导CYA注射的患者的回顾性审查.
- PP和SP组之间的内镜技术,结果和不良事件 (AE) 的比较.
- 在GV出血,干预,移植或死亡之前对患者进行随访.
主要成果:
- 主要预防组 (n=24) 与二次预防组 (n=95) 相比,经历了类似的AE和GV出血率.
- 与SP组相比,PP组的MELD得分较低,GV污名也较少.
- 在PP组中重复EUS在32%的患者中显示了残留的GV,需要重新治疗.
结论:
- 以EUS为指导的CYA注射用于胃静脉的初级预防,其安全性和有效性与二次预防相美.
- 在初级和二级预防组中,不良事件和治疗后出血率在初级和二级预防组之间类似.
- 以EUS指导的CYA注射是一种安全有效的方法,用于胃静脉的初级预防.
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