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多参数核磁共振 (MRI) 在预测尿膀新生病与病理相关性的肌肉侵入性的作用

Mrinal Tandon¹, Sumit Chakraborty², Bikramjit Barkondaj²

¹Department of Urology, IPGME&R, Kolkata, West Bengal, India.

|October 27, 2023

概括

多参数核磁共振扫描 (mp-MRI) 在确定膀癌的侵袭性方面与组织病理学有很好的一致性. 虽然mp-MRI是一种有价值的成像生物标志物,但在治疗前确定肌肉侵入性的准确性可能受到限制.

科学领域:

放射学放射学是指放射学
在瘤学瘤学.
泌尿器科泌尿器科泌尿器科泌尿器科

背景情况:

膀癌 (BC) 是全球普遍存在的恶性瘤.
准确的BC侵入性的分期对于治疗规划至关重要.

研究的目的:

评估多参数磁共振成像 (mp-MRI) 在预测膀质量侵入性的有效性.
为了比较mp-MRI发现与组织病理学检查 (HPE) 结果.

主要方法:

35名患有膀质量的患者接受了mp-MRI,包括T2加权成像 (T2WI),动态对比增强 (DCE) 和扩散加权成像 (DWI).
分析了mp-MRI结果并与HPE作为黄金标准进行了比较.
使用接收器操作特征 (ROC) 曲线分析和VI-RADS评分来评估诊断准确性.

主要成果:

mp-MRI使用VI-RADS评分>3与肌肉侵入性 (p<0.001) 有显著的相关性,具有100%的灵敏度和85.7%的特异性.
在肌肉侵入性方面,HPE分期和mp-MRI之间观察到良好的一致性.
平均明显扩散系数 (ADC) 值在低度瘤中高于高度瘤 (p=0.045).
mp-MRI在77.14%的患者中正确识别了局部T阶段,但在33.3%的病例中超过了疾病的阶段.

结论:

mp-MRI作为瘤侵入性和膀癌的成像生物标志物.
高度瘤通常更具侵入性.
对于肌肉侵入性的mp-MRI的诊断准确性有局限性,并且在TURBT和HPE之前的临床实用性需要考虑.

关键词:

表面扩散系数的明显扩散系数膀癌:膀癌是一种癌症.扩散权重成像技术的使用.多参数磁共振成像技术膀瘤的通过尿道切除.

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