个体间的大脑和行为差异适应意想不到的不确定性
Célia Soussi1,2, Sylvie Berthoz1,3, Valentine Chirokoff1,4
1INCIA CNRS 5287, University of Bordeaux, 33076 Bordeaux, France.
Biology
|October 27, 2023
概括
个人平衡利用已知的行为和探索新的行为,这个过程被称为探索/利用权衡. 这项研究揭示了在这种权衡过程中大脑连接的变化,特别是涉及皮质大脑小脑网络.
科学领域:
- 神经科学是一个神经科学.
- 认知科学 认知科学
- 决策 决策 决策 决策
背景情况:
- 适应新环境需要平衡利用已知的策略与探索新行动.
- 这种勘探/开发权衡的神经支和个体变异性,特别是关于神经连接的神经支和个体变异性,尚不清楚.
研究的目的:
- 调查神经机制,特别是内在连接模式,是探索/开发权衡的基础.
- 检查由错误反引起的环境不确定性如何影响大脑连接和行为.
- 探索神经连接变化,行为措施和焦虑等心理因素之间的相关性.
主要方法:
- 采用一种协会式学习任务,其中一个阶段引入虚假反,以创造环境不确定性.
- 休息状态功能连接 (rFC) 在任务前后被分析,以评估内在大脑连接的变化.
- 参与者根据他们的不确定性成本被分为几组,以比较rFC变化模式.
主要成果:
- 在不同不确定性成本的组之间观察到静止状态功能连接 (rFC) 变化的明显模式.
- 剥削与前带皮质和小脑区域3之间的rFC变化以及左侧和右侧额头下游回路的特定部分之间有显著的相关性.
- 焦虑和怀疑与观察到的一些rFC变化有很弱的相关性.
结论:
- 勘探/开采权衡与内在皮层-大脑连接的动态调节有关.
- 对不确定性反应的个体差异体现在大脑连接变化的独特模式中.
- 神经连接,特别是在皮质大脑电路内,在适应过程中在平衡探索和利用方面发挥着至关重要的作用.
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