Runx3 恢复可以逆转 K-Ras 激活的小鼠肺癌,并抑制复发

Ja-Yeol Lee1, Jung-Won Lee1, Tae-Geun Park1

  • 1Department of Biochemistry, School of Medicine, Institute for Tumor Research, Chungbuk National University, Cheongju 28644, Republic of Korea.

Cells
|October 27, 2023
PubMed
概括

在K-RAS激活的肺癌模型中恢复RUNX3抑制了瘤生长和复发. 这表明RUNX3是对K-RAS驱动的肺癌的持久治疗有前途的治疗标.