高压氧气疗法对抗长期COVID-19患者的氧化应激/炎症驱动症状:初步结果
Simona Mrakic-Sposta1, Alessandra Vezzoli1, Giacomo Garetto2
1Institute of Clinical Physiology, National Research Council (IFC-CNR), 20162 Milan, Italy.
高压氧疗法 (HBOT) 可以减少长期COVID-19患者的炎症和症状. 这项研究发现,HBOT减轻了氧化应激和炎症生物标志物,这表明它是长期COVID-19并发症的潜在非侵入性治疗方法.
科学领域:
- 高压医学是高压医学.
- 免疫学 免疫学 免疫学
- 在COVID-19研究中,研究人员进行了COVID-19的研究.
背景情况:
- 长期COVID-19的特点是系统性炎症和疲劳等持续症状.
- 改善氧化可以抵消炎症,提供治疗途径.
研究的目的:
- 研究高压氧疗法 (HBOT) 在长期COVID-19患者的炎症和氧化应激减轻效果.
- 评估在HBOT治疗后关键氧炎生物标志物的变化.
主要方法:
- 五名长期COVID-19患者接受了HBOT (100% O2在2.4 ATA) 与不同的协议.
- 唾液和尿液样本分析了活性氧物种 (ROS),抗氧化能力,细胞因子,脂质过氧化,DNA损伤和功能标志物.
- 在治疗前和治疗后评估生物标志物.
主要成果:
- 接受HBOT治疗导致ROS产量减弱,脂质过氧化和DNA损伤.
- 观察到炎症生物标志物水平显著降低,特别是在运动员中.
- 脏状况标志物也显示治疗后改善.
结论:
- 高压氧气疗法证明了作为长期COVID-19相关氧气炎症的非侵入性治疗的潜力.
- 通过减轻全身炎症和氧化应激,HBOT可以缓解持续症状.
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