调节肠道微生物群作为治疗听力障碍的治疗方法
Dimitri A Godur1, Alexa J Denton1,2, Nicolas Eshraghi1
1Department of Otolaryngology, Hearing Research and Cochlear Implant Laboratory, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
Audiology research
|October 27, 2023
概括
通过益生菌和特定饮食调节肠道微生物群,可以减少炎症并改善听力障碍,如感觉神经听力损失和中耳炎. 对于新的听觉干预措施,需要进一步的研究.
科学领域:
- 微生物学 微生物学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 神经科学是一个神经科学.
背景情况:
- 肠道微生物组显著影响整体健康和疾病.
- 新兴研究将肠道微生物组与听觉系统健康和听力障碍联系起来.
- 听力障碍中的炎症可以通过肠道微生物组调节来减少.
研究的目的:
- 审查有关肠道微生物组调节及其对耳部病情的影响的当前文献.
- 探索益生菌和饮食干预措施在听力健康方面的潜力.
- 评估肠道微生物组在感觉神经听力损失,中耳炎和耳中发挥的作用.
主要方法:
- 对肠道微生物组调节和听力障碍研究的文献综述.
- 对益生菌,食脂肪酸 (单不和,欧米茄-3) 和它们的影响的研究分析.
- 检查包括短链脂肪酸生产和神经递质改变在内的机制.
主要成果:
- 益生菌将碳水化合物转化为短链脂肪酸,通过维持血管供应来支持听力.
- 结合益生菌和减少抗生素治疗对中耳炎的治疗结果比单独使用抗生素更好.
- 肠道微生物组调节可以通过减少神经炎症和改变神经递质水平,使耳受益.
结论:
- 肠道微生物组调制显示出对管理听力障碍的有希望.
- 益生菌和特定的饮食可能为听力健康提供治疗效益.
- 对益生菌,天然保健产品和微量营养素的进一步研究对于开发新的听觉干预措施至关重要.
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