视频头脉冲测试中的受损视野眼镜反射在上通道脱落中的视频头脉冲测试:"自发插入"还是内淋巴流散流?
Andrea Castellucci1, Pasquale Malara2, Salvatore Martellucci3
1ENT Unit, Department of Surgery, Azienda USL-IRCCS di Reggio Emilia, 42123 Reggio Emilia, Italy.
Audiology research
|October 27, 2023
概括
上半循环通道 (SSC) 低功能的上半循环通道衰变 (SCD) 可能源于内淋巴流的消散,而不是自发的堵塞. 这表明第三个窗口机制是导致SCD患者减少前庭眼反射 (VOR) 的原因.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 神经科学是一个神经科学.
- 垂体系统生理学 垂体系统生理学
背景情况:
- 上半圆通道 (SSC) 堵塞治疗上半圆通道衰变 (SCD) 症状,但会损害前庭眼镜反射 (VOR) 收益.
- 在SCD患者中观察到SSC低功能的,空气骨间隙 (ABG) 和增强的前庭唤起肌原潜力 (VEMPs).
- 假设是自发的堵塞,但内淋巴流消散是减少SSC VOR增益的另一个建议的替代机制.
研究的目的:
- 为了比较SSC低功能的SCD患者的仪器发现与手术堵塞的SCD耳朵的术后数据.
- 为了研究SSC的潜在病理机制,VOR在SCD中的增益减少.
- 为了澄清自发堵塞和内淋巴流消散之间的争论.
主要方法:
- 视频头脉冲测试 (vHIT) 来评估SSC的VOR增益.
- 分析空气 - 骨间隙 (ABG) 值.
- 测量宫和眼前庭引起的肌源性潜能 (VEMP) 幅度和值.
- 术前SCD数据与术后手术插塞数据的比较.
主要成果:
- 在低功能的SCD耳朵和术后耳塞耳朵之间,SSC VOR增益没有显著差异 (p = 0.199).
- 经过手术的耳朵显示出后侧通道低功能的显著发展 (p = 0.002).
- 与经过手术的耳朵相比,SCD耳朵的ABG值 (p = 0.012) 和VEMP幅度 (p < 0.001) 显著更高,VEMP值 (p < 0.001) 较低.
结论:
- 在SCD中运河VOR增益的减少很可能是第三窗口机制的迹象.
- 内淋巴体流失散是SCD中SSC VOR增益减少的可能原因.
- 这些发现支持内淋巴流消散而不是自发堵塞作为SCD中减少VOR增益的病理机制.
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