药物摄入和全身疾病与牙周炎的关系:一项回顾性研究
Georgios S Chatzopoulos1,2, Ziou Jiang3, Nicholas Marka3
1Division of Periodontology, Department of Developmental and Surgical Sciences, School of Dentistry, University of Minnesota, Minneapolis, MN 55455, USA.
Journal of personalized medicine
|October 27, 2023
概括
系统性疾病,如高血压和药物,包括抗凝剂,ACE抑制剂和他类药物,与患牙周炎的风险更高有关. 这项研究强调了整体健康和牙疾病之间的潜在联系.
科学领域:
- 牙周病学 牙周病学
- 牙科公共卫生 牙科公共卫生
- 药理学 药理学是指药理学的学科.
背景情况:
- 牙周炎是一种影响牙的普遍炎症状况.
- 了解牙周炎的风险因素对于公共卫生至关重要.
- 系统性疾病和药物使用是潜在的,未被充分探索的因素.
研究的目的:
- 为了研究系统性疾病和药物使用与牙周炎之间的关联.
- 确定与牙周炎风险相关的特定疾病和药物类别.
主要方法:
- 1985年患者病历的回顾性分析.
- 数据包括人口统计,牙缺失,病情,药物摄入量和吸烟.
- 用回归模型来分析关系.
主要成果:
- 年龄较大,西班牙裔种族和黑人/西班牙裔/拉丁裔种族群体的牙周炎患病率较高.
- 高血压,玻璃眼,焦虑和抑郁症与牙周炎有关.
- 抗凝剂,他类药物和ACE抑制剂显著增加了牙周炎的几率 (分别是3.5倍,2.7倍,4.8倍).
结论:
- 系统性药物 (抗凝剂,ACE抑制剂,他类药物) 可能与牙周炎有关.
- 特定的系统性疾病 (高血压,玻璃眼,焦虑,抑郁症) 显示出与牙周炎的联系.
- 需要进一步的研究来证实这些关联在牙周炎.
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