从加工甜菜的副产品中获得的双相生物陶,用于生物活性涂料和骨填料
Miguel Suffo-Pino1, Miguel Ángel Cauqui-López2, Celia Pérez-Muñoz1
1Department of Mechanical Engineering and Industrial Design, High Engineering School, Campus Río San Pedro, University of Cádiz, Puerto Real, 11510 Cádiz, Spain.
Journal of functional biomaterials
|October 27, 2023
概括
研究人员从甜菜加工副产品中开发出一种可持续的酸生物材料. 这种生物相容材料显示出骨再生和组织工程应用的潜力.
科学领域:
- 生物材料科学 生物材料科学
- 生物矿物化 生物矿物化
- 循环经济是一个循环经济.
背景情况:
- 氧酸盐对于骨再生和植入物涂层至关重要.
- 需要可持续且具有成本效益的生物材料来进行骨增强.
- 价值化工业副产品符合循环经济原则.
研究的目的:
- 为了从Carbocal®中合成酸,这是一种CaCO3丰富的甜菜副产品.
- 为了评估合成的酸的物理化学特性和生物活性.
- 探索其作为骨填充剂和组织工程的支架的潜力.
主要方法:
- 来自Carbocal®的氧酸盐的热水合成.
- 组合分析和物理化学表征 (微观/宏观结构).
- 在体外生物活性测定 (活/死活力测试) 和与对照进行比较.
主要成果:
- 从Carbocal®中成功合成双相酸酸.
- 证明生物活性,细胞活力与阳性对照可比.
- 物理化学性能类似于天然的酸.
结论:
- 由Carbocal®衍生而来的酸是一种生物相容和生物活性材料.
- 它为骨再生应用提供了一个可持续和负担得起的替代方案.
- 作为组织工程中的支架和作为粘合性骨填充剂的潜在用途.
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