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梅塔米福普对Monopterus albus的防御系统的影响

Tianyu Guan^1,2, Yi Zhang³, Qianqian Zhu¹

¹Jiangsu Collaborative Innovation Center of Regional Modern Agriculture & Environmental Protection, Huaiyin Normal University, Huai'an 223300, China.

|October 27, 2023

概括

暴露于甲米福普除草剂会导致氧化损伤,并损害Monopterus albus的防御系统. 这项研究揭示了metamifopop的存在.

科学领域:

环境毒理学环境毒理学
水生生态毒理学水生生态毒理学
农药影响评估农药影响评估

背景情况:

田中的除草剂对非标水生生物有风险.
甲米福普被广泛使用,需要对毒性进行评估.
了解甲米福普对水生动物防御机制的影响至关重要.

研究的目的:

评估甲米福普对Monopterus albus.bus的抗氧化,免疫和亡防御系统的影响.
为了确定甲米福普在水生生物中的剂量依赖性毒性.
评估甲米福普对氧化应激标志物和炎症反应的影响.

主要方法:

白 (Monopterus albus) 被暴露在不同度的甲米 (00.8 mg/L) 中.
评估的氧化应激标志物:活性氧物种 (ROS),马隆迪化物 (MDA) 和蛋白质碳化 (PCO).
测量了抗氧化酶活性 (SOD,CAT,GPX),免疫参数 (WCN,ACP,AKP) 和与亡相关的基因表达.

主要成果:

甲米福普暴露增加了ROS,MDA和PCO,表明氧化损伤.
抗氧化酶活动显示出复杂的反应,最初增加,然后在更高度下降.
免疫参数通常被抑制,随着metamifop水平的增加,细胞亡被促进.

结论:

梅塔米福普通过增加ROS产量,诱导了Monopterus albus中显著的氧化损伤.
这种除草剂损害了鱼的抗氧化剂和免疫防御系统.
暴露于美塔米福普会促进亡,突出其对水生生物的潜在生态毒理风险.

关键词:

抗氧化作用抗氧化作用灭症 (apoptosis) 是一种死亡的过程.除草剂是一种除草剂.免疫力是一种免疫力.这是一种炎症炎症炎症炎症.氧化应激是一种氧化应激.

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