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Updated: Jul 12, 2025

Co-immunoprecipitation Assay for Studying Functional Interactions Between Receptors and Enzymes
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通过调节STING表达,SIX4控制了抗PD-1的有效性.

Beiyuan Liang1, Evan H Zhang1, Zhen Ye1

  • 1Department of Cancer Biology and Genetics, The Ohio State University, Columbus, Ohio.

Cancer research communications
|October 27, 2023
PubMed
概括

在结肠癌中SIX4调节STING的表达,影响抗瘤免疫力. 这一发现为预测免疫检查点阻塞疗法的反应提供了潜在的生物标志物.

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