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Updated: Jul 12, 2025

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VarEPS-Influ:一种流感病毒基因组发生和虚拟变化的风险评估系统

Chang Shu1,2, Qinglan Sun1,3, Guomei Fan1,3

  • 1Microbial Resource and Big Data Center, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.

Nucleic acids research
|October 27, 2023
PubMed
概括

VarEPS-Influ数据库提供了对流感病毒突变的全面风险评估,评估了当前和潜在的未来变异. 该系统有助于预测和管理流感带来的挑战.

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Viral Mutations00:36

Viral Mutations

A mutation is a change in the sequence of bases of DNA or RNA in a genome. Some mutations occur during replication of the genome due to errors made by the polymerase enzymes that replicate DNA or RNA. Unlike DNA polymerase, RNA polymerase is prone to errors because it is not capable of “proofreading” its work. Viruses with RNA-based genomes, like HIV, therefore accrue mutations faster than viruses with DNA-based genomes. Because mutation and recombination provide the raw material...
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