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Updated: Jul 12, 2025

Defining the Program of Maternal mRNA Translation during In vitro Maturation using a Single Oocyte Reporter Assay
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Defining the Program of Maternal mRNA Translation during In vitro Maturation using a Single Oocyte Reporter Assay

Published on: June 16, 2021

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通过调节母体mRNA的储存和清除,LSM14B对卵细胞中介成熟至关重要

Yanling Wan1,2,3,4, Shuang Yang5, Tongtong Li1,2,3,4

  • 1Center for Reproductive Medicine, Shandong University, Jinan, Shandong 250012, China.

Nucleic acids research
|October 27, 2023
PubMed
概括

在卵细胞生长过程中,LSM14B对存储母体mRNA在线粒体关联核糖蛋白域 (MARDO) 中至关重要. 它的缺失会扰乱mRNA清除,通过阻断介质成熟,导致女性不孕.

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