在患有或没有活跃癌症的患者中,通过导管进行大动脉置换
Tadao Aikawa1,2, Toshiki Kuno3,4, Aaqib H Malik5
1Department of Cardiology Juntendo University Urayasu Hospital Urayasu Japan.
Journal of the American Heart Association
|October 27, 2023
概括
接受过导管大动脉置换 (TAVR) 且癌症活跃的患者的住院死亡率相似,但再入院和需要输血的出血风险增加. 某些特定的癌症,如结肠癌,在TAVR后显著增加了这些风险.
科学领域:
- 心脏病学 心脏病学
- 在瘤学瘤学.
- 医疗保健服务研究 医疗服务研究
背景情况:
- 在患有活跃癌症或转移性疾病的患者中,过导管大动脉置换 (TAVR) 的临床结果数据有限.
- 了解这些结果对于优化患者护理和决策至关重要.
研究的目的:
- 调查活跃癌症对TAVR后短期死亡率,并发症和再入院率的影响.
- 为了分析各种癌症类型的这些结果.
主要方法:
- 在TAVR案件中使用了全国 Readmissions 数据库 (2012-2019).
- 根据特定的癌症类型对患者进行了分层,并分析了住院死亡率,需要输血的出血和30/90/180天的再入院.
- 根据潜在的混因素进行调整.
主要成果:
- 活跃癌症与增加的住院死亡率无关 (aOR 1.06).
- 活跃的癌症患者患有30,90和180天再入院和需要输血的30天出血的风险更高.
- 结肠癌,前列腺癌和转移性癌症独立地与增加的出血风险有关;结肠癌和转移性癌症与更高的再入院率有关.
结论:
- 接受TAVR的活跃癌症患者的住院死亡率与没有癌症的患者相似.
- 活跃癌症与TAVR后再入院和需要输血的出血风险明显更高,特定的癌症类型带来更大的风险.
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