与维护改善的射出分数相关的因素:基于心声图的注册研究
Brenna McElderry1, Thomas O'Neill2, Brian P Griffin3,4
1Department of Medicine Cleveland Clinic Cleveland OH USA.
Journal of the American Heart Association
|October 27, 2023
概括
在心力衰竭患者中保持改善的射出分数 (EF) 需要持续使用氨酸-血管氨酸-氨系统抑制剂. 某些因素,如男性性别和并发症,与最初改善后的EF下降有关.
科学领域:
- 心脏病学 心脏病学
- 心脏衰竭研究研究
背景情况:
- 改善喷射率的心力衰竭 (HFimpEF) 是一个公认的临床实体.
- 虽然 EF 改善的因素已知,但持续改善的因素尚未定义.
研究的目的:
- 在一大群患者中,识别与随着时间的推移保持改善的射出分数 (EF) 相关的因素.
主要方法:
- 对7070名HFimpEF患者和随访心声图 (≥9个月) 的回顾性分析.
- 使用了根据人口统计,并发病和药物调整的后勤回归模型.
主要成果:
- 白人种族和ACE抑制剂,ARB或RNAI的使用与持续改善的EF有关.
- 男性性别,心房动,冠状动脉疾病,心肌梗塞病史,ICD和循环利尿剂的使用与EF下降有关.
结论:
- 持续使用氨酸- ангиотензин- алдостерон系统抑制剂对于在初始恢复阶段之后保持改善的EF至关重要.
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