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慢性病的预后价值在接受左心房附属体闭塞的患者中

Domenico G Della Rocca^1,2, Michele Magnocavallo^1,3, Christoffel J Van Niekerk⁴

¹Texas Cardiac Arrhythmia Institute, St.David's Medical Center, 3000 North I-35, Suite 720, Austin, TX 78705, USA.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

|October 27, 2023

概括

慢性病 (CKD) 增加了心房动 (AF) 患者的风险,这些患者经历左心房尾闭塞 (LAAO). 中度至重度的CKD与较高的复合终点率有关,影响结果.

科学领域:

心脏病学心脏病学
腎臟病學 (nephrology) 是一種醫學專業.
干预心脏病学干预心脏病学

背景情况:

心房动 (AF) 和慢性病 (CKD) 经常同时存在.
这两种情况都会增加血栓栓塞 (TE) 的风险.
慢性病还使患者有更高的出血风险.

研究的目的:

为了评估CKD的预后意义在经过皮肤穿透左心房尾闭塞 (LAAO) 的患者中.
评估CKD不同阶段对LAAO后心血管结果的影响.

主要方法:

对2124名连续接受LAAO治疗的AF患者的分析.
根据估计的淋巴膜过率,将CKD分为1+2,3,4和5阶段.
主要终点:心血管死亡率,TE和严重出血的复合.
随访期为13个±7个月.

主要成果:

一个非显著的趋势向更高的围绕程序不良事件与恶化的CKD.
与第1+2.2阶段相比,CKD第3,4和5阶段的初级复合终点的发生率明显高于第1+2.2阶段.
在所有CKD群体中,左心房尾封闭显示出大量的TE风险降低.
在所有CKD组中观察到较大出血的相对风险降低.

结论:

中度至重度的CKD与接受LAAO的AF患者中初级复合终点的发病率增加有关.
在降低TE风险和相对大出血风险方面,LAAO的有效性在不同的CKD严重程度组中保持一致.

关键词:

心房动是一种心房动.慢性脏疾病慢性脏疾病左心房附属体是左心房的附属体一次性中风,中风.一个守望者,一个守望者.

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