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Updated: Jul 12, 2025

Continuous Fluorescence-Based Endonuclease-Coupled DNA Methylation Assay to Screen for DNA Methyltransferase Inhibitors
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化学抑制剂向致癌物 m6A 修改蛋白质

Yue Huang1,2, Wenyang Xia2,3, Ze Dong1

  • 1School of Pharmaceutical Science and Technology, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China.

Accounts of chemical research
|October 27, 2023
PubMed
概括

研究人员开发了针对FTO酶的新型化学抑制剂,FTO酶是N6-甲基氨酸 (m6A) RNA修饰的关键调节剂. 这些抑制剂对研究m6A生物学和通过调节基因表达来开发新的抗癌药物充满希望.

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